The distribution of saponins in vivo affects their synergy with chimeric toxins against tumours expressing human epidermal growth factor receptors in mice

BACKGROUND AND PURPOSE: Certain saponins synergize with antitumour drugs to enhance their efficacy, but the mechanisms underlying this synergy in vivo are not well studied. Here, we describe the distribution of Saponinum album (Spn) from Gypsophila paniculata L. in mice after subcutaneous injection....

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Bibliografiske detaljer
Main Authors: Bachran, C, Weng, A, Bachran, D, Riese, SB, Schellmann, N, Melzig, MF, Fuchs, H
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825356/
https://ncbi.nlm.nih.gov/pubmed/20015087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00543.x
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