Dose-dependent enhancement of T-lymphocyte priming and CTL lysis following ionizing radiation in an engineered model of oral cancer

OBJECTIVES: Determine if direct tumor cell cytotoxicity, antigen release, and susceptibility to T-lymphocyte killing following radiation treatment is dose-dependent. MATERIALS AND METHODS: Mouse oral cancer cells were engineered to express full-length ovalbumin as a model antigen. Tumor antigen rele...

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Udgivet i:Oral Oncol
Main Authors: Morisada, Megan, Moore, Ellen C., Hodge, Rachel, Friedman, Jay, Cash, Harrison A., Hodge, James W., Mitchell, James B., Allen, Clint T.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528171/
https://ncbi.nlm.nih.gov/pubmed/28688697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2017.06.005
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