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Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor
The identification of the kinase or kinases targeted by protein kinase inhibitors is a critical challenge in validating their use as therapeutic agents or molecular probes. Here, to address this problem, we describe a chemical genomics strategy that uses a direct comparison between microarray transc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC552777/ https://ncbi.nlm.nih.gov/pubmed/15738404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407170102 |
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