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Toll-like Receptor 4 Deficiency Reduces Oxidative Stress and Macrophage Mediated Inflammation in Hypertensive Kidney

Oxidative stress and inflammation are integral to hypertension-induced renal injury. A unifying feature for the two components is Toll-like receptors (TLR), which are key regulators of the innate immune system. Recent studies implicate TLR4 activation and oxidative stress in cardiovascular diseases...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pushpakumar, Sathnur, Ren, Lu, Kundu, Sourav, Gamon, Alejandra, Tyagi, Suresh C., Sen, Utpal
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526876/
https://ncbi.nlm.nih.gov/pubmed/28743964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06484-6
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