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Matrix metalloproteinase inhibition mitigates renovascular remodeling in salt-sensitive hypertension
Extracellular matrix (ECM) remodeling is the hallmark of hypertensive nephropathy. Uncontrolled proteolytic activity due to an imbalance between matrix metalloproteinases and tissue inhibitors of metalloproteinases (MMPs/TIMPs) has been implicated in renovascular fibrosis. We hypothesized that inhib...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804376/ https://ncbi.nlm.nih.gov/pubmed/24159376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.63 |
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