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Angiotensin-II Induced Hypertension and Renovascular Remodeling in TIMP2 Knockout Mice
Sustained hypertension induces renovascular remodeling by altering extracellular matrix (ECM) components. Matrix metalloproteinases (MMPs) are Zn-dependent enzymes that regulate ECM turnover in concert with their inhibitors, tissue inhibitors of metalloproteinases, TIMPs. Increased MMP-2 & -9 ha...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000563/ https://ncbi.nlm.nih.gov/pubmed/24077247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e3283649b33 |
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