Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying

BACKGROUND & AIMS: Depletion of interstitial cells of Cajal (ICCs) is common in diabetic gastroparesis. However, in approximately 20% of patients with diabetes, gastric emptying (GE) is accelerated. GE is also faster in obese individuals, and is associated with increased blood levels of glucose...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Gastroenterology
Κύριοι συγγραφείς: Hayashi, Yujiro, Toyomasu, Yoshitaka, Saravanaperumal, Siva Arumugam, Bardsley, Michael R., Smestad, John A., Lorincz, Andrea, Eisenman, Seth T., Cipriani, Gianluca, Nelson Holte, Molly H., Al Khazal, Fatimah J., Syed, Sabriya A., Gajdos, Gabriella B., Choi, Kyoung Moo, Stoltz, Gary J., Miller, Katie E., Kendrick, Michael L., Rubin, Brian P., Gibbons, Simon J., Bharucha, Adil E., Linden, David R., Maher, Louis James, Farrugia, Gianrico, Ordog, Tamas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2017
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526732/
https://ncbi.nlm.nih.gov/pubmed/28438610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.04.020
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