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IL-23 limits the production of IL-2 and promotes autoimmunity in lupus

The IL-23/IL-17 pathway is important in multiple autoimmune diseases, but its effect on lupus pathology remains unclear with opposing trials in murine models of the disease. Herein we show a disease activity related upregulation of serum IL-23 and IL-23 receptor in patients with SLE as compared to h...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Dai, Hong, He, Fan, Tsokos, George C., Kyttaris, Vasileios C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526729/
https://ncbi.nlm.nih.gov/pubmed/28646040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700418
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