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Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus

Decreased IL-2 production in systemic lupus erythematosus (SLE) represents a central component of the disease immunopathology. We report that the message, protein, and enzymatic activity of the catalytic subunit of protein phosphatase 2A (PP2Ac), but not PP1, are increased in patients with SLE regar...

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Detalhes bibliográficos
Main Authors: Katsiari, Christina G., Kyttaris, Vasileios C., Juang, Yuang-Taung, Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253625/
https://ncbi.nlm.nih.gov/pubmed/16224536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24895
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