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Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus

Decreased IL-2 production in systemic lupus erythematosus (SLE) represents a central component of the disease immunopathology. We report that the message, protein, and enzymatic activity of the catalytic subunit of protein phosphatase 2A (PP2Ac), but not PP1, are increased in patients with SLE regar...

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Detalles Bibliográficos
Main Authors: Katsiari, Christina G., Kyttaris, Vasileios C., Juang, Yuang-Taung, Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253625/
https://ncbi.nlm.nih.gov/pubmed/16224536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24895
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