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The Role of IL-23/IL-17 Axis in Lupus Nephritis

T cells that express IL-17 infiltrate the kidneys of patients with systemic lupus erythematosus. A significant proportion of these cells are CD3(+)CD4(−)CD8(−) double-negative T cells. In this study, we show that double-negative T cells from MRL/lpr mice express high amounts of IL-17 and that as dis...

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Autores principales: Zhang, Zheng, Kyttaris, Vasileios C., Tsokos, George C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766304/
https://ncbi.nlm.nih.gov/pubmed/19657089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900385
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