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Distinct Sequences and Post-translational Modifications in Cardiac Atrial and Ventricular Myosin Light Chains Revealed by Top-down Mass Spectrometry

Myosin is the principal component of the thick filaments that, through interactions with the actin thin filaments, mediates force production during muscle contraction. Myosin is a hexamer, consisting of two heavy chains, each associated with an essential (ELC) and a regulatory (RLC) light chain, whi...

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Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Gregorich, Zachery R., Cai, Wenxuan, Lin, Ziqing, Chen, Albert J., Peng, Ying, Kohmoto, Takushi, Ge, Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526110/
https://ncbi.nlm.nih.gov/pubmed/28427997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.04.002
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