Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury

BACKGROUND: Microglial activation and the subsequent inflammatory response in the central nervous system play important roles in secondary damage after traumatic brain injury (TBI). High-mobility group box 1 (HMGB1) protein, an important mediator in late inflammatory responses, interacts with transm...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neuroinflammation
Egile Nagusiak: Chen, Xiangrong, Wu, Shukai, Chen, Chunnuan, Xie, Baoyuan, Fang, Zhongning, Hu, Weipeng, Chen, Junyan, Fu, Huangde, He, Hefan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525354/
https://ncbi.nlm.nih.gov/pubmed/28738820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0917-3
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