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Activation of STING in T cells induces type I IFN responses and cell death
STING was initially described as a sensor of intracellular bacterial and viral DNA and a promising adjuvant target in innate immune cells; more recently STING has also been shown to detect endogenous DNA and play a role in tumor immunity and autoimmune disease development. Thus far STING has been st...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5525333/ https://ncbi.nlm.nih.gov/pubmed/28615418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601999 |
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