Novel Tmem173 allele reveals importance of STING N-terminus in trafficking and type I IFN production

With the STING C-terminus being extensively studied, the role of the N-terminal domain (NTD) of STING remains an important subject of investigation. Here we identify novel mutations in NTD of Sting of the MOLF strain in response to Herpes Simplex Virus and Listeria monocytogenes both in vitro and in...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Surpris, Guy, Chan, Jennie, Thompson, Mikayla, Ilyukha, Vladimir, Liu, Beiyun C., Atianand, Maninjay, Sharma, Shruti, Volkova, Tatyana, Smirnova, Irina, Fitzgerald, Katherine A., Poltorak, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707084/
https://ncbi.nlm.nih.gov/pubmed/26685207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501415
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