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Quantitative analysis of 3D alignment quality: its impact on soft-validation, particle pruning and homogeneity analysis
Single Particle Analysis using cryo-electron microscopy is a structural biology technique aimed at capturing the three-dimensional (3D) conformation of biological macromolecules. Projection images used to construct the 3D density map are characterized by a very low signal-to-noise ratio to minimize...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524947/ https://ncbi.nlm.nih.gov/pubmed/28740215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06526-z |
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