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PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens

Pharmacological and functional genomic screens play an essential role in the discovery and characterization of therapeutic targets and associated pharmacological inhibitors. Although these screens affect thousands of gene products, the typical readout is based on low complexity rather than genome-wi...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Bush, Erin C., Ray, Forest, Alvarez, Mariano J., Realubit, Ronald, Li, Hai, Karan, Charles, Califano, Andrea, Sims, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524642/
https://ncbi.nlm.nih.gov/pubmed/28740083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00136-z
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