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CYP2B6 516G>T Minor Allele Protective of Late Virologic Failure in Efavirenz-treated HIV-Infected Patients in Botswana

BACKGROUND: CYPB2B6 polymorphisms that affect efavirenz (EFV) concentrations are common, but the effect of this polymorphism on HIV virologic failure in clinical practice settings has not fully been elucidated. Our objective was to investigate the relationship between the CYPB2B6 516G>T genotype...

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Dades bibliogràfiques
Publicat a:J Acquir Immune Defic Syndr
Autors principals: Vujkovic, Marijana, Bellamy, Scarlett L., Zuppa, Athena F., Gastonguay, Marc, Moorthy, Ganesh S., Ratshaa, Bakgaki R., Han, Xiaoyan, Steenhoff, Andrew P., Mosepele, Mosepele, Strom, Brian L., Aplenc, Richard, Bisson, Gregory P., Gross, Robert
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524513/
https://ncbi.nlm.nih.gov/pubmed/28481785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001442
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