CYP2B6 516G>T Minor Allele Protective of Late Virologic Failure in Efavirenz-treated HIV-Infected Patients in Botswana

BACKGROUND: CYPB2B6 polymorphisms that affect efavirenz (EFV) concentrations are common, but the effect of this polymorphism on HIV virologic failure in clinical practice settings has not fully been elucidated. Our objective was to investigate the relationship between the CYPB2B6 516G>T genotype...

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Vydáno v:J Acquir Immune Defic Syndr
Hlavní autoři: Vujkovic, Marijana, Bellamy, Scarlett L., Zuppa, Athena F., Gastonguay, Marc, Moorthy, Ganesh S., Ratshaa, Bakgaki R., Han, Xiaoyan, Steenhoff, Andrew P., Mosepele, Mosepele, Strom, Brian L., Aplenc, Richard, Bisson, Gregory P., Gross, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524513/
https://ncbi.nlm.nih.gov/pubmed/28481785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001442
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