CYP2B6 516G>T Minor Allele Protective of Late Virologic Failure in Efavirenz-treated HIV-Infected Patients in Botswana

BACKGROUND: CYPB2B6 polymorphisms that affect efavirenz (EFV) concentrations are common, but the effect of this polymorphism on HIV virologic failure in clinical practice settings has not fully been elucidated. Our objective was to investigate the relationship between the CYPB2B6 516G>T genotype...

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Pubblicato in:J Acquir Immune Defic Syndr
Autori principali: Vujkovic, Marijana, Bellamy, Scarlett L., Zuppa, Athena F., Gastonguay, Marc, Moorthy, Ganesh S., Ratshaa, Bakgaki R., Han, Xiaoyan, Steenhoff, Andrew P., Mosepele, Mosepele, Strom, Brian L., Aplenc, Richard, Bisson, Gregory P., Gross, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524513/
https://ncbi.nlm.nih.gov/pubmed/28481785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001442
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