CYP2B6 516G>T Minor Allele Protective of Late Virologic Failure in Efavirenz-treated HIV-Infected Patients in Botswana

BACKGROUND: CYPB2B6 polymorphisms that affect efavirenz (EFV) concentrations are common, but the effect of this polymorphism on HIV virologic failure in clinical practice settings has not fully been elucidated. Our objective was to investigate the relationship between the CYPB2B6 516G>T genotype...

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Bibliografski detalji
Izdano u:J Acquir Immune Defic Syndr
Glavni autori: Vujkovic, Marijana, Bellamy, Scarlett L., Zuppa, Athena F., Gastonguay, Marc, Moorthy, Ganesh S., Ratshaa, Bakgaki R., Han, Xiaoyan, Steenhoff, Andrew P., Mosepele, Mosepele, Strom, Brian L., Aplenc, Richard, Bisson, Gregory P., Gross, Robert
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524513/
https://ncbi.nlm.nih.gov/pubmed/28481785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001442
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