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Optimization of the process of inverted peptides (PIPE(PLUS)) to screen PDZ domain ligands
PDZ domains play crucial roles in cell signaling processes and are therefore attractive targets for the development of therapeutic inhibitors. In many cases, C-terminal peptides are the physiological binding partners of PDZ domains. To identify both native ligands and potential inhibitors we thus ha...
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| Vydáno v: | Bioorg Med Chem Lett |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5523833/ https://ncbi.nlm.nih.gov/pubmed/28549735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.05.045 |
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