Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma

High-grade glioma (HGG) is an incurable brain cancer. The transcriptomes of cells within HGG tumors are highly heterogeneous. This renders the tumors unresponsive or able to adapt to therapeutics targeted at single pathways, thereby causing treatment failure. To overcome this, we focused on cyclin-d...

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Bibliografski detalji
Izdano u:Oncogenesis
Glavni autori: Greenall, S A, Lim, Y C, Mitchell, C B, Ensbey, K S, Stringer, B W, Wilding, A L, O'Neill, G M, McDonald, K L, Gough, D J, Day, B W, Johns, T G
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523066/
https://ncbi.nlm.nih.gov/pubmed/28504693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.33
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