Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma

High-grade glioma (HGG) is an incurable brain cancer. The transcriptomes of cells within HGG tumors are highly heterogeneous. This renders the tumors unresponsive or able to adapt to therapeutics targeted at single pathways, thereby causing treatment failure. To overcome this, we focused on cyclin-d...

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Bibliografske podrobnosti
izdano v:Oncogenesis
Main Authors: Greenall, S A, Lim, Y C, Mitchell, C B, Ensbey, K S, Stringer, B W, Wilding, A L, O'Neill, G M, McDonald, K L, Gough, D J, Day, B W, Johns, T G
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523066/
https://ncbi.nlm.nih.gov/pubmed/28504693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.33
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