Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells

Glioblastoma is deemed the most malignant form of brain tumour, particularly due to its resistance to conventional treatments. A small surviving group of aberrant stem cells termed glioma initiation cells (GICs) that escape surgical debulking are suggested to be the cause of this resistance. Relativ...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Lim, Yi Chieh, Roberts, Tara L., Day, Bryan W., Stringer, Brett W., Kozlov, Sergei, Fazry, Shazrul, Bruce, Zara C., Ensbey, Kathleen S., Walker, David G., Boyd, Andrew W., Lavin, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528585/
https://ncbi.nlm.nih.gov/pubmed/25017126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.012
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