Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells

Glioblastoma is deemed the most malignant form of brain tumour, particularly due to its resistance to conventional treatments. A small surviving group of aberrant stem cells termed glioma initiation cells (GICs) that escape surgical debulking are suggested to be the cause of this resistance. Relativ...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Lim, Yi Chieh, Roberts, Tara L., Day, Bryan W., Stringer, Brett W., Kozlov, Sergei, Fazry, Shazrul, Bruce, Zara C., Ensbey, Kathleen S., Walker, David G., Boyd, Andrew W., Lavin, Martin F.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2014
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528585/
https://ncbi.nlm.nih.gov/pubmed/25017126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.012
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