The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma.

Phospholipase C-gamma (PLC-gamma) and GTPase activating protein (GAP) are substrates of EGF, PDGF and other growth factor receptors. Since either PLC-gamma or GAP also bind to the activated receptors it was suggested that their SH2 domains are mediating this association. We attempted to delineate th...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Margolis, B, Li, N, Koch, A, Mohammadi, M, Hurwitz, D R, Zilberstein, A, Ullrich, A, Pawson, T, Schlessinger, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC552227/
https://ncbi.nlm.nih.gov/pubmed/2176151
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares