Phospholipase C-gamma, a substrate for PDGF receptor kinase, is not phosphorylated on tyrosine during the mitogenic response to CSF-1.

Quiescent mouse NIH3T3 cells expressing a transduced human c-fms gene encoding the receptor for colony stimulating factor-1 (CSF-1) were stimulated with mitogenic concentrations of platelet-derived growth factor (PDGF) or CSF-1. Immunoprecipitated phospholipase C-gamma (PLC-gamma) was phosphorylated...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Downing, J R, Margolis, B L, Zilberstein, A, Ashmun, R A, Ullrich, A, Sherr, C J, Schlessinger, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1989
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08496.x
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