Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Heparin-binding growth factors (HBGFs) bind to high-affinity cell surface receptors which possess intrinsic tyrosine kinase activity. A Mr 150,000 protein phosphorylated on tyrosine in response to class 1 HBGF (HBGF-1) was purified and partially sequenced. On the basis of this sequence, cDNA clones...

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Detalhes bibliográficos
Main Authors: Burgess, W H, Dionne, C A, Kaplow, J, Mudd, R, Friesel, R, Zilberstein, A, Schlessinger, J, Jaye, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361079/
https://ncbi.nlm.nih.gov/pubmed/2167438
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