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Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Heparin-binding growth factors (HBGFs) bind to high-affinity cell surface receptors which possess intrinsic tyrosine kinase activity. A Mr 150,000 protein phosphorylated on tyrosine in response to class 1 HBGF (HBGF-1) was purified and partially sequenced. On the basis of this sequence, cDNA clones...

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Udgivet i:Mol Cell Biol
Principais autores: Burgess, W H, Dionne, C A, Kaplow, J, Mudd, R, Friesel, R, Zilberstein, A, Schlessinger, J, Jaye, M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2167438/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4770-4777.1990
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