SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma.

Several cytoplasmic tyrosine kinases contain a conserved, non-catalytic stretch of approximately 100 amino acids called the src homology 2 (SH2) domain, and a region of approximately 50 amino acids called the SH3 domain. SH2/SH3 domains are also found in several other proteins, including phospholipa...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Rotin, D, Margolis, B, Mohammadi, M, Daly, R J, Daum, G, Li, N, Fischer, E H, Burgess, W H, Ullrich, A, Schlessinger, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1992
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556487/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1537335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05087.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi