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The IGH locus relocalizes to a “recombination compartment” in the perinucleolar region of differentiating B-lymphocytes
The immunoglobulin heavy chain (IGH) gene loci are subject to specific recombination events during B-cell differentiation including somatic hypermutation and class switch recombination which mark the end of immunoglobulin gene maturation in germinal centers of secondary lymph nodes. These two events...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522243/ https://ncbi.nlm.nih.gov/pubmed/28445143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16941 |
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