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Topologically-associating domains: gene warehouses adapted to serve transcriptional regulation

Structural-functional domains have long been hypothesized to occur in eukaryotic chromosomes, but their existence still remains controversial. Here, we discuss the current state of studies of 3D genome folding and the relation of this folding to the functional organization of the genome.

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Transcription
Päätekijät: Razin, Sergey V., Gavrilov, Alexey A., Vassetzky, Yegor S., Ulianov, Sergey V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984688/
https://ncbi.nlm.nih.gov/pubmed/27111547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1181489
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