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Topologically-associating domains: gene warehouses adapted to serve transcriptional regulation

Structural-functional domains have long been hypothesized to occur in eukaryotic chromosomes, but their existence still remains controversial. Here, we discuss the current state of studies of 3D genome folding and the relation of this folding to the functional organization of the genome.

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書誌詳細
出版年:Transcription
主要な著者: Razin, Sergey V., Gavrilov, Alexey A., Vassetzky, Yegor S., Ulianov, Sergey V.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984688/
https://ncbi.nlm.nih.gov/pubmed/27111547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1181489
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