Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene regulation. In particular, Hi-C revealed that chromosomes of animals are organized into topologically associating domains (TADs), evolutionary conserv...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Ulianov, Sergey V., Khrameeva, Ekaterina E., Gavrilov, Alexey A., Flyamer, Ilya M., Kos, Pavel, Mikhaleva, Elena A., Penin, Aleksey A., Logacheva, Maria D., Imakaev, Maxim V., Chertovich, Alexander, Gelfand, Mikhail S., Shevelyov, Yuri Y., Razin, Sergey V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691752/
https://ncbi.nlm.nih.gov/pubmed/26518482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.196006.115
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