Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila

How the nuclear lamina (NL) impacts on global chromatin architecture is poorly understood. Here, we show that NL disruption in Drosophila S2 cells leads to chromatin compaction and repositioning from the nuclear envelope. This increases the chromatin density in a fraction of topologically-associatin...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ulianov, Sergey V., Doronin, Semen A., Khrameeva, Ekaterina E., Kos, Pavel I., Luzhin, Artem V., Starikov, Sergei S., Galitsyna, Aleksandra A., Nenasheva, Valentina V., Ilyin, Artem A., Flyamer, Ilya M., Mikhaleva, Elena A., Logacheva, Mariya D., Gelfand, Mikhail S., Chertovich, Alexander V., Gavrilov, Alexey A., Razin, Sergey V., Shevelyov, Yuri Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414625/
https://ncbi.nlm.nih.gov/pubmed/30862957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09185-y
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