Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene regulation. In particular, Hi-C revealed that chromosomes of animals are organized into topologically associating domains (TADs), evolutionary conserv...

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Vydáno v:Genome Res
Hlavní autoři: Ulianov, Sergey V., Khrameeva, Ekaterina E., Gavrilov, Alexey A., Flyamer, Ilya M., Kos, Pavel, Mikhaleva, Elena A., Penin, Aleksey A., Logacheva, Maria D., Imakaev, Maxim V., Chertovich, Alexander, Gelfand, Mikhail S., Shevelyov, Yuri Y., Razin, Sergey V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691752/
https://ncbi.nlm.nih.gov/pubmed/26518482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.196006.115
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