Homoharringtonine targets Smad3 and TGF-β pathway to inhibit the proliferation of acute myeloid leukemia cells

Homoharringtonine (HHT) has long and widely been used in China for the treatment of acute myeloid leukemia (AML), the clinical therapeutic effect is significant but the working mechanism is poorly understood. The purpose of this study is to screen the possible target for HHT with virtual screening a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Jian, Mu, Qitian, Li, Xia, Yin, Xiufeng, Yu, Mengxia, Jin, Jing, Li, Chenying, Zhou, Yile, Zhou, Jiani, Suo, Shanshan, Lu, Demin, Jin, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522237/
https://ncbi.nlm.nih.gov/pubmed/28454099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16956
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