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Homoharringtonine binds to and increases myosin‐9 in myeloid leukaemia
BACKGROUND AND PURPOSE: Homoharringtonine (HHT) is a natural alkaloid isolated from various Cephalotaxus species. HHT has been used to treat acute myeloid leukaemia (AML), chronic myeloid leukaemia (CML), chronic lymphocyte leukaemia and myelodysplastic syndromes. Although HHT inhibits protein synth...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813388/ https://ncbi.nlm.nih.gov/pubmed/26448459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13359 |
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