Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells

Mitochondrial dynamics play critical roles in maintaining mitochondrial functions. Here, we report a novel mechanism for regulation of mitochondrial dynamics mediated by tristetraprolin (TTP), an AU-rich element (ARE)-binding protein. Overexpression of TTP resulted in elongated mitochondria, down-re...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Vo, Mai-Tram, Choi, Seong Hee, Lee, Ji-Heon, Hong, Chung Hwan, Kim, Jong Soo, Lee, Unn Hwa, Chung, Hyung-Min, Lee, Byung Ju, Park, Jeong Woo, Cho, Wha Ja
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522037/
https://ncbi.nlm.nih.gov/pubmed/28410208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16706
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