Casein Kinase 2 Regulates the mRNA-destabilizing Activity of Tristetraprolin

Tristetraprolin (TTP) is an AU-rich element-binding protein that regulates mRNA stability. We previously showed that TTP acts as a negative regulator of VEGF gene expression in colon cancer cells. The p38 MAPK pathway is known to suppress the TTP activity. However, until now the signaling pathway to...

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Autores principales: Lee, Won Hyeok, Lee, Hyun Hee, Vo, Mai-Tram, Kim, Hyo Jeong, Ko, Myoung Seok, Im, Yeong-Cheol, Min, Young Joo, Lee, Byung Ju, Cho, Wha Ja, Park, Jeong Woo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122216/
https://ncbi.nlm.nih.gov/pubmed/21507959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201137
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