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Casein Kinase 2 Regulates the mRNA-destabilizing Activity of Tristetraprolin
Tristetraprolin (TTP) is an AU-rich element-binding protein that regulates mRNA stability. We previously showed that TTP acts as a negative regulator of VEGF gene expression in colon cancer cells. The p38 MAPK pathway is known to suppress the TTP activity. However, until now the signaling pathway to...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122216/ https://ncbi.nlm.nih.gov/pubmed/21507959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201137 |
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