Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28

Tristetraprolin (TTP) is a AU-rich element (ARE) binding protein and exhibits suppressive effects on cell growth through down-regulation of ARE-containing oncogenes. The let-7 microRNA has emerged as a significant factor in tumor suppression. Both TTP and let-7 are often repressed in human cancers,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kim, Chae Won, Vo, Mai-Tram, Kim, Hong Kyeung, Lee, Hyun Hee, Yoon, Nal Ae, Lee, Byung Ju, Min, Young Joo, Joo, Won Duk, Cha, Hee Jeong, Park, Jeong Woo, Cho, Wha Ja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351177/
https://ncbi.nlm.nih.gov/pubmed/22210895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1302
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados