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HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure.

The HIV-1 trans-activator protein, tat, is an RNA binding protein with a high affinity for a U-rich bulge near the tip of the stem in the RNA stem-loop structure encoded by the trans-activation responsive region (TAR). A Scatchard analysis of tat binding has shown that the purified protein forms a o...

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Detalhes bibliográficos
Main Authors: Dingwall, C, Ernberg, I, Gait, M J, Green, S M, Heaphy, S, Karn, J, Lowe, A D, Singh, M, Skinner, M A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552188/
https://ncbi.nlm.nih.gov/pubmed/2249668
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