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Transfer of Tat and release of TAR RNA during the activation of the human immunodeficiency virus type-1 transcription elongation complex.

The HIV-1 trans-activator protein, Tat, is a potent activator of transcriptional elongation. Tat is recruited to the elongating RNA polymerase during its transit through the trans-activation response region (TAR) because of its ability to bind directly to TAR RNA expressed on the nascent RNA chain....

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Autori principali: Keen, N J, Churcher, M J, Karn, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170158/
https://ncbi.nlm.nih.gov/pubmed/9311986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.17.5260
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