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Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein

The interaction of the HIV-1 transactivator protein Tat with its transactivation response (TAR) RNA is an essential step in viral replication and therefore an attractive target for developing antivirals with new mechanisms of action. Numerous compounds that bind to the 3-nt bulge responsible for bin...

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Bibliografische gegevens
Hoofdauteurs: Davidson, Amy, Leeper, Thomas C., Athanassiou, Zafiria, Patora-Komisarska, Krystyna, Karn, Jonathan, Robinson, John A., Varani, Gabriele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715490/
https://ncbi.nlm.nih.gov/pubmed/19584251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900629106
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