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Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein

The pharmacological disruption of the interaction between the HIV Tat protein and its cognate transactivation response RNA (TAR) would generate novel anti-viral drugs with a low susceptibility to drug resistance, but efforts to discover ligands with sufficient potency to warrant pharmaceutical devel...

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Detalhes bibliográficos
Main Authors: Davidson, Amy, Patora-Komisarska, Krystyna, Robinson, John A., Varani, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017588/
https://ncbi.nlm.nih.gov/pubmed/20724442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq713
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