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Host Cell Interactions are a Significant Barrier to the Clinical Utility of Peptide Antibiotics
Despite longstanding promise and many known examples, antimicrobial peptides (AMPs) have failed, thus far, to impact human medicine. Based on the physical chemistry and mechanism of action of AMPs, we hypothesized that host cell interactions could contribute to loss of activity in vivo where host ce...
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| Publicado en: | ACS Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521815/ https://ncbi.nlm.nih.gov/pubmed/27797468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00843 |
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