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A Lack of Synergy Between Membrane-permeabilizing Cationic Antimicrobial Peptides and Conventional Antibiotics

The rapid rise in morbidity and mortality from drug-resistant pathogenic bacteria has generated elevated interest in combination therapy using antimicrobial agents. Antimicrobial peptides (AMPs) are a candidate drug class to advance the development of combination therapies. Although the literature i...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: He, Jing, Starr, Charles G., Wimley, William C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259837/
https://ncbi.nlm.nih.gov/pubmed/25268681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.09.010
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