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Toward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic or cytotoxic activity in living cells
We previously performed a lipid vesicle-based, high-throughput screen on a 26-residue combinatorial peptide library that was designed de novo to yield membrane permeabilizing peptides that fold into β-sheets. The most active and soluble library members that were identified permeabilized lipid vesicl...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995353/ https://ncbi.nlm.nih.gov/pubmed/23893525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22281 |
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