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Mutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers
We recently established c-Abl as a potent suppressor of triple-negative breast cancer (TNBC) progression through its reactivation of a p53:p21 signaling axis coupled to senescence. Moreover, we observed co-expression of p53 and c-Abl to be essential for normal mammary epithelial cell physiology, as...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520943/ https://ncbi.nlm.nih.gov/pubmed/28661474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.294 |
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