c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expression

We previously reported that constitutive c-Abl activity (CST-Abl) abrogates the tumorigenicity of triple-negative breast cancer cells through the combined actions of two cellular events: downregulated matrix metalloproteinase (MMP) and upregulated p21(Waf1/Cip1) expression. We now find decreased c-A...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Morrison, Chevaun D., Allington, Tressa M., Thompson, Cheryl L., Gilmore, Hannah L., Chang, Jenny C., Keri, Ruth A., Schiemann, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340126/
https://ncbi.nlm.nih.gov/pubmed/27626309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11909
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