Loss of p53 Induces Tumorigenesis in p21-Deficient Mesenchymal Stem Cells

There is growing evidence about the role of mesenchymal stem cells (MSCs) as cancer stem cells in many sarcomas. Nevertheless, little is still known about the cellular and molecular mechanisms underlying MSCs transformation. We aimed at investigating the role of p53 and p21, two important regulators...

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Detalhes bibliográficos
Main Authors: Rodriguez, Rene, Rubio, Ruth, Masip, Manuel, Catalina, Purificación, Nieto, Ana, de la Cueva, Teresa, Arriero, Mar, San Martin, Nuria, de la Cueva, Ernesto, Balomenos, Dimitrios, Menendez, Pablo, García-Castro, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657886/
https://ncbi.nlm.nih.gov/pubmed/19308294
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